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Activation of Nrf2 is required for apigenin to exert antioxidative properties in t-BHP-treated ARPE-19 cells. ELISA for SOD activity (a), CAT activity (b), GSH-PX activity (c), ROS levels (d), MDA levels (e), and T-AOC levels (f). Significance: ∗ P < 0.05 versus control, ∗∗ P < 0.01 versus control, # P < 0.05 versus t-BHP, ## P < 0.01 versus t-BHP, and & P < 0.05 versus t-BHP + apigenin + control siRNA.
