Table 3.

Comparison of Characteristics of OA Vs CPPD

	OA	CPPD
Age of onset	Later in life	Later in life
Sex bias	Women	Women
Pattern of onset	Slow, progressive	Asymptomatic or sudden, intermittent attacks
Joint symptoms	Achy, tender, minimal to no swelling	Severe pain, warmth, swelling
Joints affected	Begins unilateral, often starts with distal interphalangeal joints, or large weight bearing joints such as the hip and knee	Unilateral, often affects large joints such as the hip, knee, and wrist
Risk factors	Include obesity, previous joint trauma, congenital bone deformities	Include genetic predisposition, mineral imbalances, previous joint trauma, thyroid disease

CPPD, calcium pyrophosphate dehydrate crystal deposition disease; OA, osteoarthritis