Figure 2. Fecal metabolic profiles of Hadza and Italians.

Heat map shows the relative abundance of fecal metabolites in Hadza (orange) and Italians (blue). Fecal metabolites were filtered for significant correlation (positive or negative) with at least one genus of the gut microbiota (P < 0.05, Kendall tau correlation test). Hierarchical clustering was performed using the Pearson distance measure and Ward linkage method. P = 3 × 10⁻⁷, Fisher’s exact test. For the full name of metabolites, please see Supplementary Table S1.