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. 2016 Sep 14;6:33043. doi: 10.1038/srep33043

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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A gene network by k-mean clustering was constructed with insulin signaling pathway enrichment (red color, p = 8.2e-8). Filled colors indicate the genes up-regulated (blue circles) and down-regulated (red circles) by GEO expression analyses.