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. 2016 Sep 14;6:33043. doi: 10.1038/srep33043

Figure 7. Kv 3.2 is associated with gluconeogenesis and ER stress response, and Kv 3.2 expression is increased by metformin.

Figure 7

(A) Sk-HepI cells infected with Kv 3.2 shRNA plasmid for 48 h, followed by western blotting. (B) Sk-HepI cells infected with Kv 3.2-pCMV6 for 48 h and then treated with palmitate (24 h, 500 uM), followed by western blotting. (C) Sk-HepI cells treated with palmitate (500 uM) without metformin (3 mM) for 24 h. Sk-HepI cells were pre-treated with Metformin for 2 h before palmitate treatment, followed by western blotting. *Presents significant differences between groups at p < 0.05. All data were represented as means ± SD, n = 3. Middle-length blots and two exposures are presented in Supplementary Figure 6.