Figure 6. Asp f3 is required for A. fumigatus virulence in invasive aspergillosis.

For each strain 10 mice were immunosuppressed with cortisone acetate and intranasally infected with conidia of the WT, the asp f3 deletion strain (∆asp f3), and the complemented strain (asp f3^C). A control group of mice was treated with PBS as a negative control. The graph shows the percentage of survivors at each day after infection. The number of asterisks indicate significances in log rank tests with p-values of p < 0.0012 (**) or p < 0.0001 (***).