Figure 4.
The effects of Psm2 on platelet adhesion. Calcein-labeled washed rat platelets (5×108/mL) were preincubated with Psm2 (0.3, 0.1, 0.03, 0.01, or 0.003 mg/mL) or vehicle for at least 1 h at 37 °C and allowed to spread on fibrinogen/collagen-coated plates. The number of adherent platelets relative to control group was measured using an automated microtiter plate reader, which was expressed as adhesion (%). (A) The effects of Psm2 on platelet adhesion to fibrinogen. (B) The effects of Psm2 on platelet adhesion to collagen. The data are presented as the mean±SD. n=3. *P<0.05, **P<0.01 vs the control group.