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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1994 Dec;47(12):1123–1124. doi: 10.1136/jcp.47.12.1123

Lymphocytic gastritis, gastric adenocarcinoma, and primary gastric lymphoma.

A P Griffiths 1, J Wyatt 1, A S Jack 1, M F Dixon 1
PMCID: PMC502210  PMID: 7876391

Abstract

A series of primary gastric lymphomas and adenocarcinomas was reviewed to assess the prevalence of lymphocytic gastritis in these conditions. Lymphocytic gastritis was more prevalent in patients with gastric adenocarcinoma (16 of 130 cases; 12.3%) and primary gastric lymphoma (six of 45 cases; 13.7%) than in unselected patients undergoing endoscopy (0.83-2.5%). This suggests that these two disparate gastric tumours may share an immunological dysfunction or a common pathogenesis, and this is of interest given that Helicobacter pylori is thought to have a role in the evolution of gastric adenocarcinoma and lymphoma.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Crabtree J. E., Wyatt J. I., Sobala G. M., Miller G., Tompkins D. S., Primrose J. N., Morgan A. G. Systemic and mucosal humoral responses to Helicobacter pylori in gastric cancer. Gut. 1993 Oct;34(10):1339–1343. doi: 10.1136/gut.34.10.1339. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Dixon M. F., Wyatt J. I., Burke D. A., Rathbone B. J. Lymphocytic gastritis--relationship to Campylobacter pylori infection. J Pathol. 1988 Feb;154(2):125–132. doi: 10.1002/path.1711540204. [DOI] [PubMed] [Google Scholar]
  3. Hussell T., Isaacson P. G., Crabtree J. E., Spencer J. The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori. Lancet. 1993 Sep 4;342(8871):571–574. doi: 10.1016/0140-6736(93)91408-e. [DOI] [PubMed] [Google Scholar]
  4. Jaskiewicz K., Price S. K., Zak J., Louwrens H. D. Lymphocytic gastritis in nonulcer dyspepsia. Dig Dis Sci. 1991 Aug;36(8):1079–1083. doi: 10.1007/BF01297450. [DOI] [PubMed] [Google Scholar]
  5. Rubio C. A., Befritz R., Eriksson B., Christensson B., Duvander A., Larsson B. The topographic distribution of lymphocytic gastritis in gastrectomy specimens. APMIS. 1991 Sep;99(9):815–819. doi: 10.1111/j.1699-0463.1991.tb01265.x. [DOI] [PubMed] [Google Scholar]
  6. Wolber R., Owen D., DelBuono L., Appelman H., Freeman H. Lymphocytic gastritis in patients with celiac sprue or spruelike intestinal disease. Gastroenterology. 1990 Feb;98(2):310–315. doi: 10.1016/0016-5085(90)90819-m. [DOI] [PubMed] [Google Scholar]
  7. Wolfsen H. C., Carpenter H. A., Talley N. J. Menetrier's disease: a form of hypertrophic gastropathy or gastritis? Gastroenterology. 1993 May;104(5):1310–1319. doi: 10.1016/0016-5085(93)90339-e. [DOI] [PubMed] [Google Scholar]

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