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. 2016 Sep 13;11(1):86. doi: 10.1186/s13000-016-0538-7

Table 2.

Summary of the histopathological features of renal biopsies of the 9 patients

Ca.1 Ca.2 Ca.3 Ca.4 Ca.5 Ca.6 Ca.7 Ca.8 Ca.9
LM
 %globally sclerotic glomeruli 0/30 1/23 0/18 0/33 0/24 1/18 1/38 0/20 1/31
 %segmentally sclerotic glomeruli 0/30 0/23 0/18 0/33 0/24 0/18 1/38 0/20 1/31
 Mesangial cell proliferation + + + + + + + - +
 Mesangial matrix hyperplasia + + + + + + + + +
 Thickening of the capillary walls ++ + ++ ++ ++ ++ ++ ++ ++
 Interstitial inflammatory + + + + ± - + - -
 Focal tubular atrophy + + + + - - - - +
IF
 IgG +++ ++ +++ +++ +++ ++ ++ ++ +++
 IgA ++(f) + ++ +(f) ++ ++ ++ ++ ++
 IgG1 +/++ ± ++ - ++ + - + -
 IgG2 ± + - - ± - ± ± +
 IgG3 ± +/++ - + + - ± ± -
 IgG4 ++ ++ ++++ ++ +++ ++ ++ ++ ++
 PLA2R + + + ++ +/++ + + + +
 C3 +/++ + ++ +/++ +++ + +/++ + ++
EM
 Subepithelium EDD ++ ++ ++ ++ ++ ++ +++ ++ ++
 Mesangial area EDD ++ + + + + + ++ + +
 Extensive processes effacement ++ ++ ++ ++ +/++ + ++ ++ ++
 Mesangial matrix hyperplasia + - + + - - + - +

Note: Ca. case, f focal