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. 2016 Sep 13;18(1):203. doi: 10.1186/s13075-016-1099-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Analysis of changes in inflammation, fatty infiltration, adipocyte area, and chondrocyte clustering by vitamin D status in knee joint tissues. a Macrophage density (per square millimeter, logarithm values), triggering receptor expressed on myeloid cells (TREM)-2 mean fluorescence intensity (MFI), and adipocyte area (per square millimeter) in infrapatellar fat. b Macrophage density (per square millimeter), TREM-2 MFI, and fatty infiltration (percentage of area, logarithm values) in muscle. c Macrophage density (per square millimeter, logarithm values), TREM-2 MFI, and chondrocyte clustering (clustered/total chondrocytes, logarithm values) in articular cartilage. d Macrophage density (per square millimeter), TREM-2 MFI, and fatty infiltration (percentage of area, logarithm values) in tendon. e Macrophage density (per square millimeter), TREM-2 MFI, and fatty infiltration (percentage of area) in ligament. f Macrophage density (per square millimeter) and TREM-2 MFI in menisci. g Macrophage density (per square millimeter, logarithm values), TREM-2 MFI, and adipocyte area (per square millimeter) in suprapatellar fat. h Macrophage density (per square millimeter, logarithm values) and TREM-2 MFI in synovial membrane