TABLE I.
Baseline Patient Demographics (n = 168)
| Variable | Frequency or median (IQRa) |
|---|---|
| Age | 22.6 years (12–39) |
| Genotype | |
| SS | 121 (73%) |
| Sβ0 | 6 (4%) |
| SC | 25 (15%) |
| Sβ+ | 9 (5%) |
| Other | 5 (3%) |
| Female | 94 (57%) |
| African American | 161 (97%) |
| Tricuspid regurgitant Jet Velocity≥2.5 (m/s) | 15 (9%) |
| Avascular necrosis | 38 (23%) |
| History of stroke | 9 (5%) |
| Retinopathy | 23 (14%) |
| Number of patients with prior antibodies | 27 (16%) |
| Number of transfusions/patient | 2 (1–4; range: 1–38 Transfusions) |
| Number of units/transfusion | 2 (1–3; range: 1–15 Units) |
| Age of RBC units | 20 days (14–27; range: 2–42 days) |
a
IQR: interquartile range.