TABLE III.
Hazard Ratio Estimates of New Antibody Formation for RBC Units of Different Ages
| Age of RBCs (days) | Hazard Ratio and 95% Confidence Intervals
|
||||
|---|---|---|---|---|---|
| Day 7 | Day 14 | Day 28 | Day 42 | Day 60 | |
| 7 | 1.5 (1.15, 2.02) | 2.2 (1.32, 3.53) | 3.5 (1.71, 7.11) | 4.2 (2.05, 8.72) | 3.6 (1.53, 8.28) |
| 14 | 1.8 (1.21, 2.59) | 2.8 (1.45, 5.52) | 5.4 (2.07, 14.29) | 7.1 (2.65, 18.86) | 5.6 (1.78, 17.58) |
| 21 | 1.9 (1.24, 3) | 3.3 (1.54, 7.18) | 7.1 (2.31, 21.5) | 9.5 (3.08, 29.62) | 7.3 (1.94, 27.31) |
| 28 | 2.1 (1.27, 3.33) | 3.7 (1.6, 8.65) | 8.5 (2.5, 28.73) | 11.8 (3.42, 40.8) | 8.8 (2.07, 37.33) |
| 35 | 2.2 (1.29, 3.6) | 4.1 (1.65, 10) | 9.8 (2.66, 35.97) | 13.9 (3.72, 52.31) | 10.2 (2.17, 47.56) |
| Patients who did not receive frozen RBC units | |||||
| 7 | 1.5 (1, 2.32) | 2.1 (1.03, 4.45) | 3.4 (1.17, 9.58) | 3.8 (1.32, 11.07) | 2.9 (0.78, 10.39) |
| 14 | 1.8 (1, 3.13) | 2.8 (1.04, 7.58) | 5.2 (1.24, 21.44) | 6.2 (1.46, 26.06) | 4.1 (0.72, 23.92) |
| 21 | 1.9 (1, 3.72) | 3.3 (1.05, 10.35) | 6.6 (1.29, 34.33) | 8.2 (1.55, 43.01) | 5.2 (0.68, 38.96) |
| 28 | 2.1 (1, 4.22) | 3.7 (1.06, 12.9) | 7.9 (1.32, 47.95) | 10 (1.62, 61.36) | 6 (0.66, 55.07) |
| 35 | 2.2 (1, 4.64) | 4 (1.06, 15.32) | 9.1 (1.34, 62.14) | 11.6 (1.67, 80.84) | 6.8 (0.64, 72.03) |