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. Author manuscript; available in PMC: 2016 Sep 14.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 May 10;55(25):7176–7179. doi: 10.1002/anie.201603254

Figure 1.

Figure 1

CSA/DD cross-correlated cross-relaxation transverse rates (ηxy). Experimental values (grey bars) for the GB1-eIF4E construct before (panel A) and after (panel B) adding 4EGI-1 (200 µM, corresponding to 2× the protein concentration) are reproduced by linear combinations of the values derived from simulations 1 and 2 as described in the text. Pearson correlation coefficient and p-value are 0.80 and 3.44·10−21, and 0.89 and 9.02·10−40 for panel A and B, respectively. Only data on the eI4E chain are shown.