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. Author manuscript; available in PMC: 2017 Aug 24.
Published in final edited form as: AIDS. 2016 Aug 24;30(13):2033–2042. doi: 10.1097/QAD.0000000000001161

Fig. 2. T cells from IF subjects exhibit increased expression of ISGs and IFN-α.

Fig. 2

(A) Freshly isolated PBMC were examined by flow cytometry for percentages of CD127+ cells in total, naïve, CM and EM CD3+CD4+ T cells. (B–C) T cells were purified from freshly isolated PBMCs and gene expression of ISGs and IFN-α was analyzed by qRT-PCR. (B) Messenger RNA expression of OAS1 and MxA (IF n=10, IS n= 9, HC n= 9) ISGs (C) IFN-α mRNA analyses (IF n=9, IS n= 11, HC n= 7). Abbreviations: 2'-5'-Oligoadenylate Synthetase-1, OAS-1; Myxovirus resistance A protein, MxA; Interferon-alpha, IFN-α; immune failure, IF; immune success, IS; healthy control, HC.