Table 2.
Biomarker | Analysis method | Heterogeneity | Odd ratio (OR) | Publication bias | |||||
---|---|---|---|---|---|---|---|---|---|
I2 (%) | p-value | Overall | Lower | Upper | p-value | Begg | Egger | ||
Malignant | |||||||||
CA15-3 | Random | 98.6 | 3.7×10−30 | 2.15 | 2.00 | 2.30 | 1.8×10−10 | 0.149 | 1.0×10−5 |
CEA | Random | 97.4 | 3.1×10−25 | 1.23 | 1.09 | 1.36 | 1.8×10−21 | 0.020 | 0.149 |
Benign** | |||||||||
CA15-3 | Random | 98.8 | 2.2×10−18 | 0.17 | −0.21 | 0.54 | 0.382 | –* | –* |
Results are not available because there were too few studies;
Analysis on CEA was not performed due to the lack of studies.