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. Author manuscript; available in PMC: 2016 Sep 14.
Published in final edited form as: J Stroke Cerebrovasc Dis. 2012 Sep 30;22(7):e111–e117. doi: 10.1016/j.jstrokecerebrovasdis.2012.08.008

Table 2.

Total leukocyte count and outcome in patients with neurologic deterioration

ND–2, mean (SD) ND–1, mean (SD) ND–0, mean (SD) ND+1, mean (SD) ND+2, mean (SD)
Returned to baseline NIHSS 10.0 (4.4)
n = 15
9.6 (3.7)
n = 30
10.3 (3.6)
n = 29
10.9 (3.9)
n = 29
10.9 (3.9)
n = 26
Did not return to baseline NIHSS 8.5 (4)
n = 22
8.9 (5.4)
n = 40
9.8 (4.3)
n = 41
9.1 (3.6)
n = 35
8.8 (2.7)
n = 29
P value .199 .199 .359 .074 .038*
Length of stay (days)
 <5 9.6 (5.7)
n = 6
7.9 (2.2)
n = 18
8.5 (3.3)
n = 17
6.9 (2)
n = 16
8.4 (1.9)
n = 8
 5–8 10.4 (2.9)
n = 10
8.9 (3.0)
n = 13
10.7 (5.2)
n = 12
9.7 (4.0)
n = 9
7.8 (2.8)
n = 8
 >8 8.3 (4.2)
n = 21
9.9 (5.9)
n = 39
10.5 (3.8)
n = 41
11.2 (3.8)
n = 39
10.5 (3.6)
n = 39
P value .414 .361 .19 <.001 .058
NIHSS score at discharge
 1–7 7.5 (2.5)
n = 16
7.6 (2.3)
n = 30
8.2 (2.6)
n = 29
8.1 (2.4)
n = 29
7.7 (2.2)
n = 21
 8–14 8.8 (2.7)
n = 8
10.8 (8.1)
n = 15
11.1 (4.3)
n = 15
12.7 (3.3)
n = 11
12.5 (3.3)
n = 12
 >14 11.4 (5.8)
n = 12
9.6 (3.6)
n = 21
11.6 (4.7)
n = 21
10.5 (4.9)
n = 19
10.5 (3.7)
n = 17
P value .047* .078 .005* .001* <.001
mRS score
 0–2 6.2 (0.7)
n = 3
6.4 (4.9)
n = 10
7.1 (2.4)
n = 10
8.0 (3.0)
n = 11
7.5 (2.0)
n = 6
 3–6 9.4 (4.3)
n = 34
9.5 (4.7)
n = 59
10.4 (4.0)
n = 59
10.2 (3.9)
n = 52
10.0 (3.5)
n = 48
P value .212 .048* .013* .082 .089
Disposition
 Favorable 8.5 (2.9)
n = 23
9.2 (5.3)
n = 46
9.3 (3.6)
n = 45
9.5 (3.1)
n = 42
9.5 (3.3)
n = 36
 Unfavorable 11.0 (6.1)
n = 10
9.5 (4.3)
n = 16
11.9 (5.3)
n = 17
10.9 (5.4)
n = 16
10.0 (3.9)
n = 14
P value .117 .844 .028* .19 .596
Mortality
 Yes 10.2 (5.6)
n = 6
8.8 (2.4)
n = 13
10.4 (3.6)
n = 12
9.2 (4.8)
n = 10
9.4 (1.4)
n = 8
 No 8.9 (3.9)
n = 31
9.3 (5.2)
n = 57
9.9 (4.1)
n = 58
10.0 (3.7)
n = 54
9.9 (3.7)
n = 47
P value .498 .752 .697 .520 .738

Abbreviations: ND, neurologic deterioration; ND–2, 2 days before ND; ND–1, 1 day before ND; ND–0, day of ND; ND+1, 1 day after ND; ND+2, 2 days after ND; SD, standard deviation; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale.

Leukocyte levels measured in 109 cells/L.

*

P < .05.

P < .001.