Table 3.
Neutrophil count and outcome in patients with neurologic deterioration
| ND–2, mean (SD) | ND–1, mean (SD) | ND–0, mean (SD) | ND+1, mean (SD) | ND+2, mean (SD) | |
|---|---|---|---|---|---|
| Returned to baseline NIHSS | 7.6 (4.5) n = 15 |
6.9 (3.6) n = 30 |
7.8 (3.2) n = 29 |
7.8 (3.9) n = 29 |
8.3 (3.9) n = 26 |
| Did not return to baseline NIHSS | 6.3 (3.9) n = 22 |
6.4 (5) n = 40 |
7.5 (4.4) n = 41 |
6.9 (3.6) n = 35 |
6.8 (2.7) n = 29 |
| P value | .243 | .305 | .456 | .243 | .218 |
| Length of stay (days) | |||||
| <5 | 7.0 (5.9) n = 6 |
4.9 (1.9) n = 18 |
5.5 (3.6) n = 17 |
4.4 (1.5) n = 16 |
6.3 (2.7) n = 8 |
| 5–8 | 7.9 (3.2) n = 10 |
6.4 (2.7) n = 13 |
8.5 (3.5) n = 12 |
7.3 (4.0) n = 9 |
5.4 (2.4) n = 8 |
| >8 | 6.3 (4.1) n = 21 |
7.5 (5.5) n = 39 |
8.2 (3.4) n = 41 |
8.5 (3.7) n = 39 |
8.1 (3.5) n = 39 |
| P value | .619 | .131 | .037* | <.001† | .059 |
| NIHSS score at discharge | |||||
| 1–7 | 5.3 (2.4) n = 16 |
5.1 (2.1) n = 30 |
5.9 (2.7) n = 29 |
5.6 (2.3) n = 29 |
5.2 (2.1) n = 21 |
| 8–14 | 6.1 (2.8) n = 7 |
7.9 (7.5) n = 15 |
8.9 (4.2) n = 14 |
8.8 (4.3) n = 11 |
9.9 (3.2) n = 12 |
| >14 | 9.9 (5.9) n = 10 |
7.0 (3.8) n = 21 |
8.6 (3.7) n = 20 |
8.3 (4.4) n = 19 |
8.6 (3.6) n = 17 |
| P value | .022* | .102 | .004* | .009* | <.001† |
| mRS score | |||||
| 0–2 | 3.9 (0.64) n = 3 |
3.6 (1.2) n = 10 |
4.5 (2.6) n = 10 |
5.3 (2.7) n = 11 |
5.2 (1.6) n = 6 |
| 3–6 | 7.1 (4.2) n = 34 |
7.0 (4.6) n = 59 |
8.1 (3.9) n = 59 |
7.7 (3.8) n = 52 |
7.8 (3.5) n = 48 |
| P value | .199 | .026* | .007* | .055 | .08 |
| Disposition | |||||
| Favorable | 6.1 (2.8) n = 23 |
6.5 (4.9) n = 46 |
6.9 (3.6) n = 45 |
6.9 (3.1) n = 42 |
6.9 (3.2) n = 36 |
| Unfavorable | 9.2 (5.9) n = 10 |
7.4 (4.3) n = 16 |
9.8 (4.8) n = 17 |
8.1 (5.2) n = 16 |
8.1 (3.7) n = 14 |
| P value | .217 | .334 | .019* | .566 | .289 |
| Mortality | |||||
| Yes | 8.1 (5.6) n = 6 |
6.1 (2.4) n = 13 |
8.0 (3.9) n = 12 |
7.0 (4.2) n = 10 |
7.6 (1.7) n = 8 |
| No | 6.6 (3.9) n = 31 |
6.7 (4.8) n = 57 |
7.5 (4.0) n = 58 |
7.4 (3.7) n = 54 |
7.5 (3.6) n = 47 |
| P value | .443 | .642 | .744 | .803 | .890 |
Abbreviations: ND, neurologic deterioration; ND–2, 2 days before ND; ND–1, 1 day before ND; ND–0, day of ND; ND+1, 1 day after ND; ND+2, 2 days after ND; SD, standard deviation; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale.
Neutrophil levels measured in 109 cells/L.
*
P < .05.
†
P < .001.