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Exactness of the “color”-labeled formulation. Comparison of reference MFPT values for both folding and unfolding of all four proteins with MFPT estimates from solving the steady-state solution of the labeled rate matrix (eq 3) when the full continuous trajectories are used to assign color labels, i.e., when all available history information is used. Reference values are direct averages of first-passage times from the trajectories.
