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. Author manuscript; available in PMC: 2016 Sep 14.
Published in final edited form as: Virus Res. 2015 Jan 30;200:19–23. doi: 10.1016/j.virusres.2015.01.018

Figure 1. Effect of resveratrol and quercetin on oxidative stress and inflammatory mediator production.

Figure 1

A549 cells were either mock-infected (Ctrl) or infected with hMPV in the presence or absence of DMSO at MOI of 1 for 24h and treated or untreated with resveratrol (10–50 µM in DMSO) or quercetin (1–10 µM in DMSO). Culture supernatants were harvested to measure (A) oxidative stress marker 8-isoprostane; (B) IL-8 and RANTES (C) Since DMSO did not have any significant effect on hMPV infection, we did not include vehicle control in further experiments. Supernatants from A549 cells either uninfected (Ctrl) or infected with hMPV and treated or untreated with resveratrol (50 µM) or quercetin (10 µM) were measured for cytokines and chemokines. Results are expressed as mean ± standard error and are representative of three independent experiments. *P < 0.05 relative to hMPV-infected cells.