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. 2016 Aug 12;18(9):569–574. doi: 10.1021/acscombsci.6b00050

Figure 3.

Figure 3

Readily prepared pilot collection of 45 chiral amino alcohol-derived fragments presented with overall yields and solubility data (nd = not determined). Compounds with >0.50 mM solubilities were exposed to an assay with a 0.50 mM upper limit (see Supporting Information). (a) Amino alcohol 7 was explored solely for the 7-membered lactam family of compounds.