Table 2.
Correlations matrix between activin A, follistatin and their ratio, and other study’s parameters for all controls (n=52).
| Activin A (pg/ml) | Follistatin (ng/ml) | Activin A to Follistatin ratio |
|
|---|---|---|---|
| Age (years) | 0.52 (<0.001)* | 0.20 (0.15) | 0.18 (0.22) |
| BMI (kg/m2) | 0.01 (0.92) | −0.16 (0.27) | 0.18 (0.20) |
| Waist circumference (cm) | −0.03 (0.82) | −0.04 (0.79) | 0.06 (0.69) |
| AST (U/l) | 0.05 (0.75) | −0.17 (0.22) | 0.16 (0.27) |
| ALT (U/l) | −0.19 (0.18) | −0.13 (0.35) | 0.00 (1.00) |
| AST/ALT ratio | 0.29 (0.15) | −0.05 (0.83) | 0.14 (0.50) |
| GGT (U/l) | −0.39 (0.005)* | −0.22 (0.11) | −0.09 (0.54) |
| Total cholesterol (mg/dl) | 0.12 (0.42) | 0.08 (0.60) | 0.05 (0.75) |
| HDL-C (mg/dl) | 0.17 (0.24) | −0.17 (0.25) | 0.21 (0.15) |
| LDL-C (mg/dl) | 0.15 (0.31) | 0.09 (0.51) | 0.07 (0.65) |
| Triglycerides (mg/dl) | −0.17 (0.42) | 0.01 (0.96) | −0.10 (0.48) |
| Urea (mg/dl) | 0.33 (0.10) | 0.09 (0.67) | 0.19 (0.35) |
| Creatinine (mg/dl) | −0.17 (0.41) | −0.40 (0.042)* | 0.13 (0.53) |
| Uric acid (mg/dl) | 0.08 (0.60) | −0.13 (0.40) | 0.09 (0.54) |
| Glucose (mg/dl) | −0.06 (0.70) | −0.10 (0.47) | 0.02 (0.91) |
| Insulin (µU/ml) | 0.08 (0.60) | −0.10 (0.50) | 0.15 (0.31) |
| HOMA-IR | 0.06 (0.68) | −0.09 (0.54) | 0.12 (0.39) |
| Leptin (ng/ml) | 0.18 (0.21) | 0.10 (0.49) | 0.10 (0.49) |
| Adiponectin (µg/ml) | 0.53 (<0.001)* | 0.06 (0.67) | 0.31 (0.027)* |
| RBP-4 (µg/ml) | −0.29 (0.036)* | −0.08 (0.57) | −0.13 (0.36) |
| Chemerin (ng/ml) | −0.03 (0.82) | 0.16 (0.26) | −0.12 (0.42) |
| Irisin (ng/ml) | −0.18 (0.21) | 0.15 (0.78) | −0.33 (0.016)* |
| Activin A (pg/ml) | - | 0.02 (0.88) | 0.63 (<0.001)* |
| Follistatin (ng/ml) | - | - | −0.73 (<0.001)* |
Data are presented as Spearman’s rho coefficient (p-value).
*
: Correlations with p-value<0.05.
Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; BMI, body mass index; GGT, gamma-glutamyl transferase; HDL-C, high density lipoprotein cholesterol; HOMA-IR, homeostatic model of assessment insulin resistance; LDL-C, low density lipoprotein cholesterol; NAFLD, nonalcoholic fatty liver disease; RBP, retinol-binding protein.