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pSphK1 positive ratio in breast cancer tissue compared with HER2 overexpression. (A) pSphK1 positive ratio were determined in the patients with HER2 overexpression/amplification negative or positive. (B) Immunohistochemistry with HER2 and pSphK1 for patients with HER2 overexpression. All five cases of HER2 overexpression displayed pSphK1 negative status.
