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. 2016 Aug 17;36(4):1837–1844. doi: 10.3892/or.2016.5023

Figure 4.

Figure 4

Effect of miR-205 mimic, miR-205 inhibitor and miR-195 mimic, miR-195 inhibitor on glioma cell proliferation. (A) Proliferation of U87 transfected respectively with miRNA mimic, inhibitor or control was detected and photographed by cell colony formation assay. (B) Relative colony formation rate was calculated in U87 cells transfected with miR-205 mimic, miR-205 inhibitor or corresponding controls. (C) Relative colony formation rate was calculated in U87 cells transfected with miR-195 mimic, miR-195 inhibitor or corresponding controls. (D) Cell viability was detected in U87 cells transfected with miR-205 mimic, miR-205 inhibitor or corresponding controls. (E) Cell viability was detected in U87 cells transfected with miR-195 mimic, miR-195 inhibitor or corresponding controls. (F) Invasive ability of U87 cells transfected with miR-205 mimic, miR-205 inhibitor or corresponding controls was detected by Transwell invasion assay. (G) Invasive ability of U87 cells transfected with miR-195 mimic, miR-195 inhibitor or corresponding controls was detected by Transwell invasion assay. (H) Proliferation of U87 cells treated with TGF-β1 and its inhibitor, LY364947. (I) Relative colony formation rate was calculated in U87 cells treated with TGF-β1 and LY364947. (J) Cell viability was detected in U87 cells stimulated by TGF-β1 and LY364947. (K) Cell invasion was determined in U87 cells stimulated by TGF-β1 and LY364947.