TABLE 2.

Public and private investments in research by disease area^a

PRIVATE PHARMACEUTICAL R&D EXPENDITURES
DISEASE AREA	EXPENDITURE (BILLIONS 2014 US$)
Bipolar	0.07
MDD	0.40
COPD	0.37
RA	0.37
Schizophrenia	0.49
Neurology	1.19
Diabetes	1.91
CVD	3.06
Cancer	20.87
Totalb	28.73

FEDERAL APPROPRIATIONS FOR BIOMEDICAL RESEARCH
2014 APPROPRIATION (BILLIONS)	APPROPRIATION (BILLIONS, 2014 US$)
Alcohol abuse and alcoholism	0.44
Drug abuse	1.00
Aging	1.05
Mental health	1.40
Neurological disorders and stroke	1.54
DDKD	1.85
Heart, lung, and blood	2.92
Allergy and infectious disease	4.26
Cancer	4.81
Totalb	19.25

^aBased on author’s calculations and various PhRMA reports^16-23

^bTotal across these nine disease areas only

BPD: bipolar disorder; COPD: chronic obstructive pulmonary disorder; CVD: cardiovascular disease; DDKD: diabetes, digestive, and kidney diseases; MDD: major depressive disorder; RA: rheumatoid arthritis