Table 2.

Variegated pattern of naturally processed B^*07;02-restricted epitope recognition by smallpox vaccines^*

Amino acid sequence**	ORF	B*07;02-positive volunteers$
FPYEGGKVF	E9L526–534				456
FPRSMLSIF	L4R37–45	222
SPSNHHILL	A3L192–200			291	823
FPKNDFVSF	B8R70–79		534		539		673
RPRDAIRFL	E2L216–224		367
RPNQHHTIDL	N2L104–113		576
APASSLLPAL	A4L126–135				392
FPSVFINPI	E9L175–183				332		689
VPITGSKLIL	G2R140–149			158	9074	278	736
YPSNKNYEI	A11R22–30			144	8701	238	1383
LPSNVEIKAI	I6L282–291				1317		438
IPKYLEIEI	A20R162–170						722
NPSKMVYALL	E5R131–140			291	1725
NPSVLKILL	B25R78–86						681
RPSTRNFFEL	D1R808–817			624	2235

^*See Ref. [34^•] for details.

^**Anchor residues are in bold.

^$Interferon-γ spot-forming cells over background per million volunteer peripheral blood mononuclear cells. Intensity of red, hierarchy within an individual; green, no response.