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Short-circuit current (ISC) response to amiloride and pimozide. (A and B) At t = 0, amiloride (10 μM) was added to apical fluid of (A) Atp1b1F/F MAECM (n = 3) and (B) Atp1b1Sftpc-cre MAECM (n = 3). After 60 minutes, pimozide (10 μM) was added to apical fluid. (C and D) At t = 0, pimozide (10 μM) was added to apical fluid of (C) Atp1b1F/F MAECM (n = 3) and (D) Atp1b1Sftpc-cre MAECM (n = 3). After 60 minutes, amiloride (10 μM) was added to apical fluid.
