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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Metabolism. 2016 Jul 30;65(10):1570–1581. doi: 10.1016/j.metabol.2016.07.012

Figure 4.

Figure 4

Effect of hyperglycemia-hyperlipidemia on retinal dysfunction. ERG was performed in dark-adapted 6–40 weeks (Wks) old ZDF rats (ZDF) and lean rats (LN) using Ocuscience HMsERG system. A dark-adapted intensity-response series was recorded using a series of Ganzfeld flashes with intensities ranging from 100–25,000 mcd.s/m^2. Representative plots at 10,000 mcd.s/m^2 from 6, 12 and 20 weeks old ZDF (black) and lean (blue) are shown. (b) Amplitude of ‘b’ wave and implicit time, obtained from 6 weeks old lean rats are considered as 100%. The results are representative of 5 or more rats in each age group. *p< 0.05 vs age-matched lean rats.