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. 2016 Sep 14;11(9):e0162645. doi: 10.1371/journal.pone.0162645

Table 1. Comparison of demographics and comorbidity between gastric disease with H pylori eradication and controls.

Control (N = 21788) Early HP Eradication (N = 2721) Late HP Eradication (N = 2726) Total (N = 5447)
n % n % n % n % p-value
Age, year 0.99
≤49 10560 48.5 1518 55.8 1122 41.2 260 48.5
50–65 7228 33.2 834 30.7 973 35.7 1807 33.2
≥65 4000 18.4 369 13.6 631 23.2 1000 18.4
Mean (SD) # 50.6 14.7 48.5 13.9 53.6 14.3 51.1 14.3 0.03
Sex 0.99
Female 8528 39.1 1019 37.5 1113 40.8 2132 39.1
Male 13260 60.9 1702 62.6 1613 59.2 3315 60.9
Comorbidity
CAD 2038 9.35 286 10.5 647 23.7 933 17.1 <0.001
Alcohol-related illness 673 3.09 132 4.85 216 7.92 348 6.39 <0.001
Stroke 621 2.85 64 2.35 116 4.26 180 3.30 0.08
COPD 1449 6.65 200 7.35 483 17.7 683 12.5 <0.001
Asthma 957 4.39 127 4.67 288 10.6 415 7.62 <0.001
Rheumatoid arthritis 26 0.12 6 0.22 7 0.26 13 0.24 0.04
Medication
Steroid used 820 3.76 117 4.30 269 9.87 386 7.09 <0.001

Chi-square test compared to total gallstone

#Two sample t-test.