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. 2016 Sep 14;11(9):e0162645. doi: 10.1371/journal.pone.0162645

Table 4. Trends of Osteoporosis risks by stratified follow-up years.

Control (N = 21788) Early HP Eradication (N = 2721) IRR * Adjusted HR Late HP Eradication (N = 2726) IRR* Adjusted HR
Follow time, years Case Rate# Case Rate# (95% CI) (95% CI) Case Rate# (95% CI) (95% CI)
≤5 years 405 4.62 75 6.67 1.44 (1.29, 1.62)*** 1.69 (1.32, 2.16)*** 109 10.3 2.23 (2.02, 2.46)*** 1.72 (1.38, 2.14)***
>5 years 159 4.87 23 4.76 0.98 (0.82, 1.16) 1.14 (0.73, 1.77) 27 8.35 1.71 (1.46, 2.01)*** 1.62 (1.06, 2.47)*

Rate#, incidence rate, per 1000 person-years; IRR *, incidence rate ratio; Adjusted HR: multiple analysis including age, sex, and co-morbidities of CAD, alcohol-related illness, stroke, COPD, asthma, rheumatoid arthritis

*p<0.05

***p<0.001