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. 2016 Sep 14;11(9):e0162766. doi: 10.1371/journal.pone.0162766

Fig 2. BrPerk KO mice are impaired in the delay match-to place working memory task.

Fig 2

(A) Spatial reference memory test in radial-arm water maze. BrPerk KO mice exhibited normal reference memory in a 4 day reference platform task in radial-arm water maze (WT n = 5, BrPerk KO n = 6). Each mouse was given 8 trials per day during the 4 day task. A trial block represents the average number of errors of 4 trials. Only male mice were used in the experiment. (B) The delay match-to-place task in radial-arm water maze. BrPerk KO mice made more errors and required longer escape latency than their wild-type littermates to locate the hidden platform in the match trial (WT n = 16, BrPerk KO n = 20; *** p<0.001, ** p<0.01, two-tailed student’s t-Test). Impaired spatial working memory was observed in BrPerk KO group in both genders. The figures represent pooled results of both genders.