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. 2016 Sep 14;11(9):e0162178. doi: 10.1371/journal.pone.0162178

Table 3. Multivariate analysis for risk factors of bacteremia during the early transplant period of tandem HDCT/auto-SCT.

Potential risk factors Gram-positive bacteremia Gram-negative bacteremia
OR 95% CI p-value OR 95% CI p-value
Second HDCT/auto-SCT (compared to the first) 0.72 0.21~2.49 0.604 0.67 0.32~1.40 0.286
Inclusion of TBI and/or thiotepa in HDCT regimen 6.28 1.34~29.50 0.020 0.60 0.29~1.26 0.178
Infused CD34+ cells <2 × 106/kg 3.35 1.02~10.98 0.046 1.40 0.63~3.12 0.416
Age at transplantation >100 months 0.93 0.26~3.29 0.911 2.56 1.25~5.24 0.010

OR, odds ratio; CI, confidence interval; HDCT/auto-SCT, high-dose chemotherapy and autologous transplantation; TBI, total body irradiation.