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Schematic of a suggested experiment for testing the contribution of the motif environment to the dynamics of Sox2 binding. A: Different sequences will be tested: 30 bp sequence containing Sox2 known motif, GT‐rich 443 bp sequences containing the known motif, and AT‐rich 443 bp sequences containing the motif. B: We propose that Sox2 dwell times will increase for the preferred AT‐rich, long sequences.
