. 2016 Sep 14;11(9):e0162378. doi: 10.1371/journal.pone.0162378

Table 2. Association between miR-224 expression and clinicopathological parameters of cervical cancer.

Clinicopathological parameters	Total(n = 126)	miR-224 expression		χ²	P value
		high	low
		31	95
Age, years
≦35	11	3	8	0.046	0.83
≧35	115	28	87	0.046	0.83
FIGO stage
I	86	16	70	5.255	0.027
II	40	15	25	5.255	0.027
Pathological grade
Grade1	3	1	2	2.91	0.127
Grade2	105	22	83
Grade3	18	8	10
Tumor size
≤4	106	22	84	9.268	0.005
>4	20	9	11	9.268	0.005
Lymph node metastasis
Negative	116	25	91	5.006	0.04
Positive	10	6	4	5.006	0.04
Vascular involvement
Negative	101	21	80	4.653	0.038
Positive	25	10	15	4.653	0.038
Deep stromal invasion
<66%	85	16	69	5.255	0.027
≧66%	41	15	26	5.255	0.027
vaginal wall extention
yes	14	5	9	1.048	0.33
no	112	26	86	1.048	0.33
parametrail extention
yes	6	2	4	0.063	0.83
no	120	29	91	0.063	0.83

FIGO: International Federation of Gynecology and Obstetrics