Fig 4. Molecular docking study on binding pattern of PA and cyclosporine (known calcineurin inhibitor) with calcineurin.

(a) Interaction of PA (blue color ligand) binding with calcineurin (green color protein) at Gln at 55^th position and Pro at 52^nd position (depicted with red color). Interaction of cyclosporine (blue color ligand) binding with calcineurin (green color protein) at Gln at 55^th position and Met 117^th position (depicted with red color). (b) Binding specificities and interaction of calcineurin (Cnb1p regulatory unit) with PA.