Table 2. ARQ 087 GI50 in Ba/F3 transfected cell lines.
Kinase | GI50 (nM) | Kinase | GI50 (nM) |
---|---|---|---|
FGFR3-BAIAP2L1 | 34.9 | FGFR2-CCD6 | 1121 |
FGFR2-CIT | 39.5 | FYN | 1329 |
TEL-FGFR2 | 59.8 | FGFR3 | 1337 |
FGFR2 | 232 | FGFR4 | 1346 |
ARG | 247 | FLT4 (VEGFR3) | 1354 |
LCK | 287 | LYN | 1363 |
FGFR2-AFF3 | 337 | PDFGR-β | 1376 |
FGFR2-CASP7 | 349 | FLT1 (VGFR1) | 1407 |
FGFR1 | 355 | PDFGFR-α | 1567 |
KIT | 474 | IGF1R | 1546 |
FGFR2-BICC1 | 990 | KDR (VEGFR2) | 1557 |
RET | 991 | FMS | 1710 |
SRC | 1091 | EphA1 | 5381 |