Table 4. ARQ 087 induces a G1 cell cycle arrest in cancer cells.

24 Hours		Cell Cycle (% cells)
Cell Line	Treatment	Sub-G1	G1	S	G2/M
NCI-H716	DMSO	1.7	35.1	42.0	21.2
	ARQ 087 0.1 μM	0.9	74.6	16.4	8.1
	ARQ 087 1.0 μM	3.1	66.5	22.7	7.8
SNU-16	DMSO	0.0	29.2	54.7	16.1
	ARQ 087 0.1 μM	0.1	37.4	49.2	13.3
	ARQ 087 1.0 μM	0.0	68.5	25.1	6.4
72 Hours		Cell Cycle (% cells)
Cell Line	Treatment	Sub-G1	G1	S	G2/M
NCI-H716	DMSO	2.0	47.2	41.7	9.1
	ARQ 087 0.1 μM	3.8	60.9	28.0	7.3
	ARQ 087 1.0 μM	17.5	60.6	19.4	2.5
SNU-16	DMSO	0.0	41.5	46.2	12.3
	ARQ 087 0.1 μM	0.0	38.5	56.1	5.4
	ARQ 087 1.0 μM	0.0	76.7	17.5	5.7