Table 1. Demographic, clinical and biological features of HD patients at baseline.
| Characteristics | Study population (n = 156) |
|---|---|
| Age (years) | 47.8 ± 11.2 |
| Age at onset (years) | 41.6 ± 11.4 |
| Sex, Men/Women | 76/80 |
| Number of CAG repeats | 45.1 ± 3.9 |
| Body Mass Index (kg/m²) | 22.8 ± 3.7 |
| Level of education (years) | 12.0 ± 3.2 |
| UHDRS functional assessment | |
| Functional checklist (25–50) | 29.8 ± 5.4 |
| Independence scale (100 to 10) | 82.0 ± 16.0 |
| TFC score (13 to 0) | 9.9 ± 2.9 |
| UHDRS Total Motor Score (out of 124) | 35.2 ± 24.4 |
| UHDRS Total Behavioural Score (out of 88) | 13.3 ± 11.2 |
| IGF-1 (ng/mL) | 156.4 ± 55.5 |
| IGFBP-3 (μg/mL) | 4.8 ± 1.1 |
| Insulin (mUI/L) | 5.0 ± 0.9 |
| Glycaemia (mmol/L) | 11.5 ± 13.6 |
CAG: cytosine-adenine-guanine; UHDRS: Unified Huntington’s Disease Rating Scale; TFC: Total Functional Capacity; IGF-1: insulin-like growth factor-I; IGFBP-3: insulin-like growth factor -binding protein 3. Results are presented in means ± standard deviation.