Table 1. Fatty acid composition of cardiolipin from HT-1080 cells after treatment of chemotherapy drugs.
| Control | Starvation | Methotrexate | Mitomycin C | Vincristine | |
|---|---|---|---|---|---|
| ACL | 17.67 ± 0.01 | 17.29 ± 0.02 | 17.82 ± 0.04 | 17.59 ± 0.01 | 17.49 ± 0.02 |
| DBI | 111.23 ± 0.68 | 99.73 ± 1.35 | 115.68 ± 1.48 | 105.21 ± 0.36 | 102.44 ± 0.64 |
| PI | 35.07 ± 0.84 | 27.12 ± 1.72 | 38.36 ± 1.73 | 28.24 ± 0.42 | 26.36 ± 0.62 |
| SFA | 2.84 ± 0.10 | 6.78 ± 0.19 | 1.72 ± 0.05 | 3.02 ± 0.11 | 4.09 ± 0.23 |
| UFA | 97.16 ± 0.10 | 93.22 ± 0.19 | 98.28 ± 0.05 | 96.98 ± 0.11 | 95.91 ± 0.23 |
| MUFA | 5.57 ± 0.04 | 5.81 ± 0.08 | 5.36 ± 0.08 | 5.93 ± 0.04 | 5.95 ± 0.05 |
| PUFA | 91.59 ± 0.10 | 87.40 ± 0.18 | 92.92 ± 0.13 | 91.05 ± 0.10 | 89.96 ± 0.22 |
| PUFAn-3 | 0.98 ± 0.09 | 0.77 ± 0.06 | 0.92 ± 0.05 | 0.62 ± 0.03 | 0.64 ± 0.02 |
| PUFAn-6 | 23.65 ± 0.25 | 17.51 ± 0.71 | 27.01 ± 0.78 | 20.33 ± 0.31 | 19.02 ± 0.49 |
Average chain length (ACL), double bond index (DBI), peroxidizability index (PI) and polyunsaturated fatty acid (PUFA) are shown. PUFAn-3: FA 18:3, 20:5, 22:5, 22:6; PUFAn-6: FA 18:2, 20:3, 20:4, 22:4, 20:2; Results in triplicate are shown as mean ± SD.