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. 2016 Aug 2;24(8):1435–1443. doi: 10.1038/mt.2016.137

Figure 1.

Figure 1

Cytokine expression from adenoviral vectors in vitro and in vivo. (a) Schematic of adenovirus construct containing murine cytokine genes under the cytomegalovirus (CMV) promoter. (b) Cytokine concentrations in cell culture supernatants 48 hours after infection. Tumor and serum levels of (c) mIL2, (d) mTNFα, (e) mIFNg, and (f) mIFNb were measured from B16.OVA tumor-bearing mice 72 hours after intratumoral injection of cytokine-coding viruses or unarmed control virus Ad5Luc1. Horizontal lines, mean values.