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. 2016 Jul 12;24(8):1492–1501. doi: 10.1038/mt.2016.101

Figure 2.

Figure 2

The antibodies against vaccinia virus in the sera of patients right before treatment and 22 days PT. The anti-VV antibodies as measured by enzyme-linked immunosorbent assays (ELISA). (a) The data were collected on sera from patients who received the virus dose at 1.0E9 PFU (n = 3). The “vaccinated control” indicated a healthy volunteer from our laboratory who was vaccinated with smallpox vaccine 5 years ago and served as a control to patients who had been vaccinated 54–76 years ago. (b) The data were collected on sera from patients who received the virus dose at 3.0E9 PFU (n = 3). (c) Shown are another presentation on the mean values when the sera were diluted at 1: 5,120. Data on D0 (day 0) provided the baseline and the data on D22 (day 22) post-treatment showed increased titers of antisera as determined by ELISA assays. The data are mean ± SD from six patients treated at two higher doses of the virus.