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. 2016 Jul 12;24(8):1492–1501. doi: 10.1038/mt.2016.101

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Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Cytokine levels in plasma. Cytokine concentrations in the plasma collected before and 4 hours after vvDD treatment were determined via Luminex assays. (a) The whole panel of cytokines assayed. All cytokines were analyzed on a logarithmic scale except those denoted by * were analyzed using the Box-Cox transformation method. * indicated adjusted P values based on log-transformed values. (b) Key inflammatory cytokines (IL-6 and IL-8). (c) Th1 (IL-2, IFN-γ, and TNF-α) and Th1-related (IL-7 and GM-CSF) cytokines. (d) Th2 cytokines (IL-4, IL-5, and IL-13). Pre-T: pretreat; Post-T: 4 hours post-treatment. The P values in the graphs are indicated, *P < 0.05; **P < 0.01; ns: no significant.