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. 2016 Aug 30;5(8):e358. doi: 10.1038/mtna.2016.70

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Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Expression of nucleolin in RB tumor samples and cell lines. (a) Fold changes in gene expression of NCL in various primary cells and cell lines. (b) Immunohistochemistry of the normal retina section (i, ii), RB tissue sections (iii, iv). (c) Expression of NCL in the cytoplasmic fraction of RB tumor tissues by immunoblotting for NCL and β-actin, graph on the right shows the densitometry analysis of tumor samples normalized to normal retina (NR). (d) Scatter plots show the expression of NCL and the NCL-APT binding to RB tumor (RB cells from the enucleated eyes). The error bar represents the SD and the * indicates significance of P < 0.05 and ** indicates significance of P < 0.001 when compared to the normal retina.