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. 2016 Aug 30;5(8):e358. doi: 10.1038/mtna.2016.70

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Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy

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Effect of NCL-APT on cell proliferation. NCL-APT and LNA-NCL-APT were assessed at the concentration of 1, 5, 10, and 20 μmol/l on the cell lines after 48 hours of treatment. Graph showing the percentage cell viability exhibited by the NCL-APT (a) and LNA-NCL-APT (b) on Y79, WERI-Rb1 and MIO-M1 cells at 48 hours using MTT assay. The Scrambled aptamer is treated at the concentration of 5 and 20 μmol/l. (c). Graph showing the cell viabilities upon scrambled aptamer treatment assessed by MTT assay. The mean of triplicate data ± SD are plotted and the * indicates significance of P < 0.05, ** indicates significance of P < 0.001 and NS indicates not significant.