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. 2016 Aug 30;5(8):e358. doi: 10.1038/mtna.2016.70

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Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Antitumor effect of NCL-APT and LNA-NCL-APT on Y79 xenograft model. (a) Graph showing the change in percentage tumor growth inhibition of the groups injected with NCL-APT and LNA-NCL-APT subcutaneously near the tumor site and LNA-NCL-APT by intraperitoneal route. Photographs showing the representative animals (b) and excised tumors (c) showing the changes in tumor growth upon treatment by s.c. and i.p. routes. The error bar in panel A represents the SEM and the * indicates significance of P < 0.05 and ** indicates significance of P < 0.001.