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DESI MS imaging of aptamer treated RB cell lines. (a) DESI-MS spectra of Y79, WERI-Rb1 and MIO-M1 cells grown in cell. Cells were washed with 1XPBS twice and spotted on Whatmann membrane and imaged using methanol as solvent using positive mode and data acquired from 50 to 2,000 Daltons. Changes in the lipid expression accompanying the treatment with nucleolin aptamer in RB cell line, Y79 (b) WERI-Rb1 (c).
