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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Addict Biol. 2016 Mar 14;22(4):977–990. doi: 10.1111/adb.12386

Figure 2. Context-induced reinstatement at different withdrawal periods (Exp. 1).

Figure 2

Left panel: between-subjects assessment. Right panel: within-subjects assessment. (A) Extinction responding: Total number of active lever presses in rats tested in the extinction context (context B, with cue) after 1 day, 1 week, or 1 month of withdrawal. (B) Extinction time course: Number of active lever presses over six 1-h extinction sessions in rats tested in context B (with cue) after 1 day, 1 week, or 1 month of withdrawal. (C) Context-induced reinstatement: Total number of active lever presses in rats tested in context A (1 h) and the last h of extinction in context B after 1 day, 1 week, or 1 month of withdrawal. * Differences between 1 day and 1 month, # differences between 1 day and 1 week, p<0.05.