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. 2016 Jan 14;68(5):1873–1884. doi: 10.1007/s10616-015-9940-3

Table 1.

Wound healing mediators quantified by multiplex ELISA

Mediators Functions References
Chemokines
 CXCL1/GRO-α NC, Ang, Epith, TR Spiekstra et al. (2007)
 CXCL5/ENA-78 NC, Ang, Mit Põld et al. (2004)
 CXCL8/IL-8 Proinflam, Ang, Epith Spiekstra et al. (2007)
 CCL2/MCP1 MC, Ang, Epit, TR Spiekstra et al. (2007)
 CCL5/RANTES Mit, MC, Epit Spiekstra et al. (2007)
 CCL 11/eotaxin Proinflam, EC, Ang Garcia-Zepeda et al. (1996)
Cytokines
 IL-6 Proinflam, Gran, Ang, Mit, Epith Spiekstra et al. (2007)
 G-CSF Proinflam, Ang Sheridan et al. (1992)
 GM-CSF Proinflam, Epith, Ang Matsuguchi et al. (1998)
 IL-1α Proinflam, Epith Ishigame et al. (2006)
 TNF-α Proinflam, Epith Spiekstra et al. (2007)
 VCAM-1 Proinflam Collins et al. (2000)
 ICAM-1 Proinflam Collins et al. (2000)
Growth factors
 HGF TR, Epith, Gran, Ang Spiekstra et al. (2007)
 VEGF-α Ang Spiekstra et al. (2007)
 FGF-β Ang, TR, Gran Donnez et al. (1998)
 TGF-β Proinflam, Gran, TR, Ang Knebelmann et al. (1998)
 PDGF-BB Ang, TR, Gran Raines et al. (1989)
 EGF Epith, Gran Libermann et al. (1985)

Ang angiogenic, TR tissue remodelling, NC inflammatory chemokine for neutrophils, MC inflammatory chemokine for monocye/macrophages, EC inflammatory chemokine for eosinophil, Epith epithelization, Proinflam proinflammatory, Gran granulation tissue stimulating, Mit mitogen