Table 1.
Mediators | Functions | References |
---|---|---|
Chemokines | ||
CXCL1/GRO-α | NC, Ang, Epith, TR | Spiekstra et al. (2007) |
CXCL5/ENA-78 | NC, Ang, Mit | Põld et al. (2004) |
CXCL8/IL-8 | Proinflam, Ang, Epith | Spiekstra et al. (2007) |
CCL2/MCP1 | MC, Ang, Epit, TR | Spiekstra et al. (2007) |
CCL5/RANTES | Mit, MC, Epit | Spiekstra et al. (2007) |
CCL 11/eotaxin | Proinflam, EC, Ang | Garcia-Zepeda et al. (1996) |
Cytokines | ||
IL-6 | Proinflam, Gran, Ang, Mit, Epith | Spiekstra et al. (2007) |
G-CSF | Proinflam, Ang | Sheridan et al. (1992) |
GM-CSF | Proinflam, Epith, Ang | Matsuguchi et al. (1998) |
IL-1α | Proinflam, Epith | Ishigame et al. (2006) |
TNF-α | Proinflam, Epith | Spiekstra et al. (2007) |
VCAM-1 | Proinflam | Collins et al. (2000) |
ICAM-1 | Proinflam | Collins et al. (2000) |
Growth factors | ||
HGF | TR, Epith, Gran, Ang | Spiekstra et al. (2007) |
VEGF-α | Ang | Spiekstra et al. (2007) |
FGF-β | Ang, TR, Gran | Donnez et al. (1998) |
TGF-β | Proinflam, Gran, TR, Ang | Knebelmann et al. (1998) |
PDGF-BB | Ang, TR, Gran | Raines et al. (1989) |
EGF | Epith, Gran | Libermann et al. (1985) |
Ang angiogenic, TR tissue remodelling, NC inflammatory chemokine for neutrophils, MC inflammatory chemokine for monocye/macrophages, EC inflammatory chemokine for eosinophil, Epith epithelization, Proinflam proinflammatory, Gran granulation tissue stimulating, Mit mitogen