Fig. 4.

Changes in relative conductance induced by the addition of ATP, ADP, or AMP. The relative macroscopic conductance G _r indicates that ATP (a) and ADP (b) were more efficient inhibitors compared to AMP (c). The relative conductance values represented by symbols in the plots are reported as mean ± SD from three independent experiments. The conductance data, fitted to the Hill equation (full line), yielded the following parameters: (i) ATP: IC₅₀ = 4.53 ± 0.07 mM and n = 4.15 ± 0.2, (ii) ADP: IC₅₀ = 8.92 ± 0.07 mM and n = 3.43 ± 0.16, and (iii) AMP: IC₅₀ = 13.43 ± 0.08 mM and n = 1.62 ± 0.17