Table 4(a).
Estimated cost of isoflurane and sevoflurane for a cardiac surgical procedure lasting 4.5 hr in 2009 (in Canada)
| Agent | Vaporizer setting (1 MAC) |
Fresh Gas Flow (L·min−1) |
Duration of Case (min) (4.5 hr) |
Molecular weight (g) | Cost ($ ·mL−1) |
Density (g·mL−1) | Cost (Canadian dollars) |
|---|---|---|---|---|---|---|---|
| isoflurane | 1.15 | 2 | 270 | 184.4 | 0.13 | 1.5 | $4.24 |
| sevoflurane | 2.0 | 2 | 270 | 200.1 | 1.00 | 1.5 | $58.92 |
MAC = minimum alveolar concentration
Using the equation: Cost (dollars) = PFTMC / (2,412 · d) 32 Where, P = vaporizer concentration, F = fresh gas flow, T = duration of anesthesia, M = molecular weight, C = cost per mL, d = density, 2,412: a constant to reflect the calculation being done at a temperature of 21°C