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| Cycles | Number |
|---|---|
| Median | 6 |
| Range | 1–31 |
| >3 | 77 |
| 3 | 4 |
| 2 | 9 |
| 1 | 12 |
| Dose modifications | n (%) |
| Started with full dose of all drugs | 33 (32.4) |
| Started with reduced dose of 1 or more drugs | 69 (67.6) |
| Reduction or omission of 5-FU bolus | 93% |
| Reduction in irinotecan | 88% |
| Reduction in oxaliplatin | 68% |
| Reduction infusional 5-FU | 66% |
